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Study three focused on skin radiance and texture, with 65% of subjects reporting visible improvement in fine lines

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MC1R AND ITS ROLE IN SKIN CANCER The melanocortin-1 receptor (MC1R) is a G-protein coupled 7-membrane spanning receptor (GPCR) that was originally described on cells of melanocytic origin, but is also present on keratinocytes, fibroblasts and most immune cells, suggesting that it can influence innate and adaptive immunity (81, 82)