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GLP-1 receptor agonists are increasingly used to treat type 2 diabetes and obesity, and trials have shown reductions in cardiovascular risk and slowing of kidney failure. Adverse events are mostly gastrointestinal.

Interventions: Deep diaphragmatic breathing (5-10 minutes before meals) Vagal nerve stimulation (gargling, humming, cold exposure) Adaptogenic herbs (ashwagandha, rhodiola) if stress is chronic When to Worry: Red Flags While constipation is common, certain symptoms require prompt medical attention: Unexplained weight loss Blood in stool Severe bloating or pain Vomiting Constipation lasting more than 2 weeks despite intervention Consult your provider if any of these are present

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