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These modifications include lasting changes in chromatin accessibility and transcriptional programs in intestinal epithelial stem cells, which may persist into adulthood ( Enterococcus faecalis , a member of the gut microbiota, to migrate to the bone marrow, where it induces trained immunity in myeloid progenitors via the Mincle receptor

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Mulligan et al 36 examined the impact of vitamin D deficiencies on inflammation in a mouse model of CRS involving aspergillus fumigatus