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It is noteworthy that these multifaceted non-enzymatic roles do not function in isolation, their mechanistic foundation lies in the direct regulation of extracellular matrix (ECM) physicochemical properties and signaling molecule homeostasis [7], with functional realization being highly dependent on this specific microenvironment

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Sleep fragmentation and shortened sleep duration result in increased pro-inflammatory activity of the immune system, including sustained activation of the NF-κB pathway, which modulates stress responses and contributes to the persistence of autoimmune inflammation (Irwin et al., 2008

Carnitine is a substance found naturally in all cells of the body