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Glutamine–glutamate imbalance in the pathogenesis of cardiovascular disease | Nature Cardiovascular Research

elegans fed DB in the presence of 15 mM NAC had a shortened lifespan comparable to those fed LB without NAC supplementation (Fig

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[DOI] [PubMed] [Google Scholar] 65.Ye H, Jeong SY, Ghosh MC, Kovtunovych G, Silvestri L, Ortillo D, Uchida N, Tisdale J, Camaschella C, Rouault TA, Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts, J Clin Invest, 120 (2010) 1749–1761