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This approach accounts for: Targeted physiological effect Side effect profile Metabolic individuality Specific clinical indication By integrating these parameters, clinicians can design a scientifically grounded, safe, and individualized antioxidant protocol — ensuring that glutathione therapy remains both effective and personalized.

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IF has been shown to enhance the gene expression of certain M2 macrophage markers, partly through increasing adiponectin levels [95, 99]