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This relation was explicitly applied to the estimation of acid dissociation constants by Waldron in the 1950s57 and by Kiso et al in the 1960s58 using a paper strip as a supporting medium

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Effect of host derived glutathione on disease susceptibility of host cells to Frog Virus 3 To explore whether changes in host cell glutathione cause a generalised effect on disease susceptibility, the above experiment was repeated with a ranavirus as an alternative amphibian pathogen