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As the budding sprouts move along the higher concentration of VEGF, the tip cells attach to the extracellular matrix (ECM) via integrin and migrate to the signal molecules such as semaphorin and ephrin

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Sizes:28 pcs

This work was supported by grants from the NIH, NSF, DOD, ACS, the National Foundation for Cancer Research and the Whitaker Foundation (R.K.J.), and from the VIB, FWO, Biomed and the VLK (P.C.)