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Future frameworks must integrate Safe-by-Design (SbD) paradigms, combining risk assessment with sustainability metrics like process mass intensity (PMI) to holistically optimize nanoparticle production [337, 338]

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Size:90 Softgel

Variations in the MYOC gene sequence lead to the most common form, characterized by elevated IOP, whereas rare mutations in OPTN and copy number variations in TBK-1 (TANK-binding protein 1) can cause familial NTG (normal tension glaucoma) (Stuart et al., 2023)