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The study was also registered with ClinicalTrials.gov, NCT03818737

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topical or systemic steroids might be necessary for Esomeprazole 20-May-2021 l INDICATIONS AND DOSE Peptic ulcer disease ▶ BY MOUTH ▶ Adult: 20 mg once daily for 4–8 weeks NSAID-associated gastric ulcer ▶ BY MOUTH ▶ Adult: 20 mg once daily for 4–8 weeks ▶ BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION Adult: 20 mg daily continue until oral administration possible, injection to be given over at least 3 minutes Prophylaxis of NSAID-associated gastric ulcer in patients with an increased risk of gastroduodenal complications who require continued NSAID treatment ▶ ▶ BY MOUTH ▶ Adult: 20 mg daily (Books-Courses-Medical Applications) Gastric and duodenal ulceration 83 Prophylaxis of NSAID-associated gastric or duodenal ulcer ▶ BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION Adult: 20 mg daily continue until oral administration possible, injection to be given over at least 3 minutes Gastro-oesophageal reflux disease (in the presence of erosive reflux oesophagitis) ▶ ▶ BY MOUTH ▶ ▶ ▶ Child 1–11 years (body-weight 10–19 kg): 10 mg once daily for 8 weeks Child 1–11 years (body-weight 20 kg and above): 10–20 mg once daily for 8 weeks Child 12–17 years: Initially 40 mg once daily for 4 weeks, continued for further 4 weeks if not fully healed or symptoms persist