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In another study, it was shown that, under oxidative stress conditions, Ku 70 and Ku 80 were degraded by the activated caspase-3 in the pancreatic acinar cells, whereas S -glutathionylation of procaspase-3 blocked its activation and regulated the activities of Ku indirectly [91]

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This reduces the amount of synovial fluid , the lubricating fluid that cushions the joint

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